Cinta Bladé Selected Research

Proanthocyanidins (Procyanidins)

4/2014	Grape seed proanthocyanidin extract improves the hepatic glutathione metabolism in obese Zucker rats.
1/2014	Differential modulation of apoptotic processes by proanthocyanidins as a dietary strategy for delaying chronic pathologies.
1/2012	Chronic dietary supplementation of proanthocyanidins corrects the mitochondrial dysfunction of brown adipose tissue caused by diet-induced obesity in Wistar rats.
8/2011	Improvement of mitochondrial function in muscle of genetically obese rats after chronic supplementation with proanthocyanidins.
4/2011	Modulatory effect of grape-seed procyanidins on local and systemic inflammation in diet-induced obesity rats.
1/2011	Proanthocyanidins modulate microRNA expression in human HepG2 cells.
7/2010	Lipogenesis is decreased by grape seed proanthocyanidins according to liver proteomics of rats fed a high fat diet.
1/2010	Hypolipidemic effects of proanthocyanidins and their underlying biochemical and molecular mechanisms.
7/2009	Dietary procyanidins enhance transcriptional activity of bile acid-activated FXR in vitro and reduce triglyceridemia in vivo in a FXR-dependent manner.
3/2009	Inhibitory effects of grape seed procyanidins on foam cell formation in vitro.

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Cinta Bladé Research Topics

Disease

17	Obesity 01/2020 - 01/2006
9	Body Weight (Weight, Body) 11/2018 - 10/2010
7	Cardiovascular Diseases (Cardiovascular Disease) 01/2020 - 10/2008
7	Metabolic Syndrome (Dysmetabolic Syndrome X) 04/2015 - 07/2009
6	Inflammation (Inflammations) 01/2020 - 03/2009
5	Insulin Resistance 01/2014 - 01/2006
4	Atherosclerosis 12/2013 - 03/2005
3	Type 2 Diabetes Mellitus (MODY) 01/2012 - 07/2009
2	Neoplasms (Cancer) 05/2020 - 01/2014
2	Dyslipidemias (Dyslipidemia) 06/2017 - 07/2010
2	Heart Diseases (Heart Disease) 04/2015 - 01/2006
2	Hypertriglyceridemia 07/2009 - 10/2008
1	Hypersensitivity (Allergy) 05/2020
1	Seasonal Affective Disorder 01/2018
1	Jet Lag Syndrome 06/2015
1	Neurodegenerative Diseases (Neurodegenerative Disease) 01/2014
1	Mental Disorders (Mental Disorder) 01/2014
1	Hyperlipidemias (Hyperlipidemia) 01/2014
1	Hypertension (High Blood Pressure) 12/2013
1	Metabolic Diseases (Metabolic Disease) 10/2013
1	Chronic Disease (Chronic Diseases) 01/2013
1	Mitochondrial Diseases (Mitochondrial Disease) 01/2012
1	Diabetes Mellitus 01/2012
1	Polycystic Ovary Syndrome (Syndrome, Stein-Leventhal) 01/2011
1	Fatty Liver 05/2010
1	Non-alcoholic Fatty Liver Disease 05/2010
1	Weight Gain 01/2006

Drug/Important Bio-Agent (IBA)

12	Proanthocyanidins (Procyanidins)IBA 04/2014 - 01/2006
9	proanthocyanidinIBA 01/2020 - 08/2011
5	Glucose (Dextrose)FDA LinkGeneric 01/2018 - 01/2006
5	FlavonoidsIBA 01/2014 - 01/2006
5	procyanidinIBA 04/2011 - 10/2008
4	CholesterolIBA 04/2015 - 03/2009
4	PolyphenolsIBA 10/2014 - 03/2009
4	AntioxidantsIBA 04/2014 - 04/2011
3	CytokinesIBA 01/2020 - 03/2009
3	LeptinIBA 01/2020 - 01/2016
3	LipidsIBA 01/2018 - 01/2006
3	Fatty Acids (Saturated Fatty Acids)IBA 10/2014 - 11/2012
3	Reactive Oxygen Species (Oxygen Radicals)IBA 04/2014 - 12/2013
2	Proteins (Proteins, Gene)FDA Link 05/2020 - 07/2010
2	ResveratrolIBA 01/2020 - 11/2018
2	Grape Seed ProanthocyanidinsIBA 09/2018 - 07/2010
2	Biomarkers (Surrogate Marker)IBA 06/2017 - 05/2010
2	Glutathione (Reduced Glutathione)IBA 04/2014 - 11/2011
2	lardIBA 01/2014 - 07/2012
2	Pharmaceutical PreparationsIBA 01/2012 - 07/2010
2	Triglycerides (Triacylglycerol)IBA 05/2010 - 10/2008
1	NickelIBA 05/2020
1	Peptides (Polypeptides)IBA 05/2020
1	Cardiotonic Agents (Cardiac Stimulants)IBA 01/2020
1	Catechin (Z 7300)IBA 01/2020
1	Gallic AcidIBA 01/2020
1	Biological ProductsIBA 06/2017
1	Unsaturated Fatty Acids (Polyunsaturated Fatty Acids)IBA 10/2014
1	Grape Seed ExtractIBA 10/2013
1	MicroRNAs (MicroRNA)IBA 01/2013
1	Hypoglycemic Agents (Hypoglycemics)IBA 01/2012
1	Dipeptidyl Peptidase 4 (Dipeptidyl Peptidase IV)IBA 01/2012
1	Dipeptidyl-Peptidase IV InhibitorsIBA 01/2012
1	oleoyl-estrone (oleoyl estrone)IBA 11/2011
1	EnzymesIBA 11/2011
1	Glutathione Transferase (Glutathione S-Transferase)IBA 11/2011
1	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 04/2011
1	C-Reactive ProteinIBA 04/2011
1	Pioglitazone (Actos)FDA Link 01/2011
1	Flutamide (Eulexin)FDA LinkGeneric 01/2011
1	Oxidants (Oxidizing Agents)IBA 01/2011
1	Metformin (Glucophage)FDA LinkGeneric 01/2011
1	Sulfides (Thioethers)IBA 07/2010
1	sulfide quinone reductaseIBA 07/2010
1	ProteomeIBA 07/2010
1	Phospholipases (Phospholipase)IBA 07/2010
1	Liver ExtractsIBA 05/2010
1	Dietary CholesterolIBA 05/2010
1	LigandsIBA 07/2009
1	Therapeutic UsesIBA 07/2009
1	AdipokinesIBA 03/2009
1	Apolipoproteins B (ApoB)IBA 10/2008
1	ApolipoproteinsIBA 10/2008
1	Cytoplasmic and Nuclear Receptors (Nuclear Receptors)IBA 10/2008
1	Lipoproteins (Lipoprotein)IBA 03/2005

Therapy/Procedure

1	Oral Administration 10/2008